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| Movie | BlacKkKlansman | Dr. Kennebrew Beauregard | 2018-08-10 |
| Movie | Mission: Impossible - Fallout | Alan Hunley | 2018-07-27 |
| Movie | The Boss Baby | Boss Baby | 2017-03-31 |
| Movie | Concussion | Dr. Julian Bailes | 2015-12-25 |
| Movie | Mission: Impossible - Rogue Nation | Alan Hunley | 2015-07-31 |
| Movie | Still Alice | John Howland | 2015-02-20 |
| Movie | Blue Jasmine | Hal | 2013-08-23 |
| Movie | Rise of the Guardians | North | 2012-11-21 |
| Movie | To Rome with Love | John | 2012-07-06 |
| Movie | Rock of Ages | Dennis Dupree | 2012-06-15 |
| Movie | My Sister's Keeper | Campbell Alexander | 2009-06-26 |
| Movie | Lymelife | Mickey Bartlett | 2009-11-12 |
| Movie | It's Complicated | Jake Adler | 2009-12-25 |
| Movie | Madagascar: Escape 2 Africa | Makunga | 2008-11-07 |
| Movie | My Best Friend's Girl | Professor Turner | 2008-09-19 |
| Movie | The Good Shepherd | Sam Murach | 2006-12-22 |
| Movie | Running with Scissors | Norman Burroughs | 2006-10-27 |
| Series | 30 Rock | Jack Donaghy / ... 138 episodes, 2006-2013 | 2006-10-11 |
| Movie | The Departed | Ellerby | 2006-10-06 |
| Movie | Fun with Dick and Jane | Jack McCallister | 2005-12-21 |
| Movie | Elizabethtown | Phil Devoss | 2005-10-14 |
| Movie | The Cooler | Shelly Kaplow | 2004-01-16 |
| Movie | The Aviator | Juan Trippe | 2004-12-25 |
| Movie | Along Came Polly | Stan Indursky | 2004-01-16 |
| Movie | The SpongeBob SquarePants Movie | Dennis | 2004-11-19 |
| Movie | The Cat in the Hat | Quinn | 2003-11-21 |
| Movie | The Royal Tenenbaums | Narrator | 2002-01-04 |
| Movie | Final Fantasy: The Spirits Within | Captain Gray Edwards | 2001-07-11 |
| Movie | Pearl Harbor | Lt. Col. James Doolittle | 2001-05-25 |
| Series | Clerks | Leonardo Leonardo 5 episodes, 2000-2001 | 2000-05-31 |
| Movie | Mercury Rising | Nick Kudrow | 1998-04-03 |
| Movie | The Edge | Robert Green | 1997-09-26 |
| Movie | The Juror | Teacher | 1996-02-02 |
| Movie | The Shadow | Lamont Cranston / The Shadow | 1994-07-01 |
| Movie | The Getaway | Carter 'Doc' McCoy | 1994-02-11 |
| Movie | Malice | Jed | 1993-10-01 |
| Movie | Glengarry Glen Ross | Blake | 1992-10-02 |
| Movie | The Hunt for Red October | Jack Ryan | 1990-03-02 |
| Movie | Great Balls of Fire! | Jimmy Swaggart | 1989-06-30 |
| Movie | Talk Radio | Dan | 1989-01-13 |
| Movie | Working Girl | Mick Dugan | 1988-12-21 |
| Movie | Beetlejuice | Adam | 1988-03-30 |
| Movie | She's Having a Baby | Davis McDonald | 1988-02-05 |